Amiosin

Indonesia • Dexa Medica

Indication

Amikacin is indicated in the short-term treatment of serious infection due to susceptible strains of Gram-negative and Gram-positive bacteria.

  • Septicemia (including neonatal sepsis)
  • Serious infections of the respiratory tract
  • Bone and joint infections
  • Central nervous system infections (including meningitis)
  • Skin and soft tissue infections
  • Intra-abdominal infections (including peritonitis)
  • Infections of the burns
  • Postoperative infections (including post-vascular surgery)
  • Serious complicated and recurrent urinary tract infections

Composition

Amikacin 500 mg

Package

5 vials of 2 ml

Dosage Forms

Injection

ATC Classification

J01G

Warning

Alcohol
Consult Your Doctor
Safety of this item for use with alcohol has not been established. Please consult your doctor.
Machinery
Consult Your Doctor
Safety of this item for use while operating heavy machinery has not been established. Please consult your doctor.
Pregnancy
Consult Your Doctor
Safety of this item for use during pregnancy has not been established. Please consult your doctor.
Lactation
Not Recommended
This item is not safe for use during lactation.

Dosage

0 to 1 Year Old

Initial dose 10 mg/kg/day to be followed with 7.5 mg/kg every 12 hours.

1 to 18 Years Old

Children and older infants with normal renal function: 15 mg/kg/day divided into 2 or 3 equal doses.

18 Years Old and Above

500 mg twice daily. The maximum total dose for adults: 15 g.

Other Details

The usual duration of treatment is 7 to 10 days. The total daily dose should not exceed 15 mg/kg/day or 1.5 g/day.

Patients with Impaired Renal Function

Daily dose may be reduced or prolonged intervals to avoid the drug accumulation. The initial dose is 7.5 mg/kg. Recommendation of the method to estimate dose in patients known or expected impaired renal function can be calculated by multiplying serum (in mg/100ml) creatinine concentration by 9 and the result is a dosage interval in hours.