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Canderin 16mg tablets

Dexa Medica

Ingredients in every tablet

Candesartan 16 mg

Each package contains

3 blisters of 10 tablets

Dosage form

tablet

Dosage formTablet; plain

Flavour

None

W.H.O. classification

C09C
C09C

A.T.C. Level 1

Anatomical Main group

C - Cardiovascular system
C09C

A.T.C. Level 2

Therapeutic subgroup

C09 - Agents Acting on the Renin-Angiotensin System
C09C

A.T.C. Level 3

Pharmacological subgroup

C09C - Angiotensin II Receptor Blockers (Arbs); Plain

Available in

Indonesia

Warnings

Alcohol

CONSULT YOUR DOCTORSafety of this item for use with alcohol has not been established. Please consult your doctor.

Machinery

CAUTIONThis item may not be safe for use while operating heavy machinery. Use with caution and after consultation with your doctor.

Pregnancy

NOT RECOMMENDEDThis item is not safe for use during pregnancy.

Lactation

NOT RECOMMENDEDThis item is not safe for use during lactation.

Indication

Hypertension
Treatment of patients with heart failure and impaired left ventricle systolic function (left ventricular ejection fraction ≤ 40%) when ACE-inhibitors are not tolerated.

Dosage

0 TO 18 YEARS OLD
The safety and efficacy of candesartan have not been established in children and adolescents (under 18 years).

18 TO 65 YEARS OLD
— Dosage in hypertension:
The initial dose is 4 mg once daily. The dose should be adjusted according to response, with a maximum dose of 16 mg daily. The maximum effect is achieved within about 4 weeks after initiating therapy.

— Dosage in heart failure:
The usual recommended initial dose is 4 mg once daily. Up-titration to the target dose of 32 mg once daily or the highest tolerated dose is done by doubling the dose at intervals of at least 2 weeks.

65 YEARS OLD AND ABOVE
No initial dosage adjustment is necessary in elderly patients.

ADMINISTRATION
Candesartan should be taken once daily with or without food. Candesartan can be administered with other antihypertensive drugs.

PATIENTS WITH HEPATIC IMPAIRMENT
Dosage in hypertension:
An initial dose of 2 mg once daily is recommended in patients with mild to moderate hepatic impairment. The dose may be adjusted according to response. There is no experience in patients with severe hepatic impairment.

Dosage in heart failure:
No initial dose adjustment is necessary in patients with mild to moderate hepatic impairment.

PATIENTS WITH RENAL IMPAIRMENT
Dosage in hypertension:
No initial dosage adjustment is necessary in mild renal impairment. A lower initial dose of 2 mg once daily is suggested for patients with moderate and severe renal impairment. The dose may be adjusted according to response.

Dosage in heart failure:
No initial dose adjustment is necessary for patients with renal impairment.