Human Albumin 20% 50 ml
Indication
Increase in oncotic pressure in case of oncotic deficiency. Diluted as a 4-5% solution for iso-oncotic volume replacement with long-term effect. Therapy of albumin deficiency.
Composition
Human Albumin 10.000 mg
Package
Dosage Forms
ATC Classification
Warning
Dosage
For All Ages
Human albumin can be administered by the intravenous route, either undiluted or after dilution in an isotonic solution (e.g. 5% glucose or 0.9 % sodium chloride).
Albumin solutions must not be diluted with water for injections as this may cause haemolysis in recipients. The infusion rate should be adjusted according to the individual circumstances and the indication.
In plasma exchange the infusion-rate should be adjusted to the rate of removal. If large volumes are administered, the product should be warmed to room or body temperature before use. Do not use solutions which are cloudy or contain residues (deposits/particles). This may indicate that the protein is unstable or that the solution has become contaminated
Other Details
The dose required depends on the size of the patient, the severity of trauma or illness and on continuing fluid and protein losses. Measures of adequacy of circulating volume and not plasma albumin levels should be used to determine the dose required.
If human albumin is to be administered, hemodynamic performance should be monitored regularly; this may include:
- arterial blood pressure and pulse rate
- central venous pressure
- pulmonary artery wedge pressure
- urine output
- electrolyte
- haematocrit/haemoglobin