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Isorane inhalation vapour

Marketed by Dexa Medica

Ingredients in every vial

Isoflurane 250 ml

Each package contains

1 bottle of 250 ml

Dosage form

inhalation vapour

Dosage formInhalation vapour; solution

Flavour

None

W.H.O. classification

N01A
N01A

A.T.C. Level 1

Anatomical Main group

N - Nervous system
N01A

A.T.C. Level 2

Therapeutic subgroup

N01 - Anesthetics
N01A

A.T.C. Level 3

Pharmacological subgroup

N01A - Anesthetics; General

Available in

Indonesia

Warnings

Alcohol

CONSULT YOUR DOCTORSafety of this item for use with alcohol has not been established. Please consult your doctor.

Machinery

NOT RECOMMENDEDThis item should not be used while operating heavy machinery.

Pregnancy

NOT RECOMMENDEDThis item is not safe for use during pregnancy.

Lactation

NOT RECOMMENDEDThis item is not safe for use during lactation.

Indication

General inhalation anaesthetic for use in induction and maintenance.

Dosage

INDUCTION
Isoflurane with oxygen or with an oxygen/nitrous oxide mixture may be used for induction, but more usually a short-acting barbiturate or other intravenous induction agent is administered followed by inhalation of the isoflurane mixture.

It is recommended that induction with isoflurane be initiated at a concentration of 0.5%. Concentrations of 1.5 to 3.0% usually produce surgical anesthesia in 7 to 10 minutes.

MAINTENANCE
Surgical levels of anesthesia may be maintained with 1.0-2.5% isoflurane in oxygen/nitrous oxide mixtures. An additional 0.5-1.0% isoflurane may be required when given with oxygen alone.

Arterial pressure levels during maintenance tend to be inversely related to alveolar isoflurane concentrations in the absence of other complicating factors. Excessive falls in blood pressure may be due to depth of anesthesia and, in these circumstances, should be corrected by reducing the inspired isoflurane concentration.

Induced hypotension can be achieved by artificially ventilating patients with isoflurane 2.5-4.0%. Pre-treatment with clonidine significantly decreases the isoflurane requirement for maintaining induced hypotension.

ADMINISTRATION
it is recommended that isoflurane should be vaporized using a flow through vaporizer specifically calibrated for the agent, though non-calibrated vaporizers may be used, particularly with low-flow or closed systems, in conjunction with equipment capable of monitoring inspired or expired concentrations.