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Tranexid 10% injection

Dexa Medica

Ingredients in every 5 ml

Tranexamic acid 500 mg

Each package contains

10 ampoules of 5 ml

Dosage form

injection

Dosage formInjection

Flavour

None

W.H.O. classification

B02A
B02A

A.T.C. Level 1

Anatomical Main group

B - Blood and blood forming organs
B02A

A.T.C. Level 2

Therapeutic subgroup

B02 - Antihemorrhagics
B02A

A.T.C. Level 3

Pharmacological subgroup

B02A - Antifibrinolytics

Available in

Indonesia

Warnings

Alcohol

CONSULT YOUR DOCTORSafety of this item for use with alcohol has not been established. Please consult your doctor.

Machinery

CONSULT YOUR DOCTORSafety of this item for use while operating heavy machinery has not been established. Please consult your doctor.

Pregnancy

CAUTIONThis item may not be safe for use during pregnancy. Use with caution and after consultation with your doctor.

Lactation

CAUTIONThis item may not be safe for use during lactation. Use with caution and after consultation with your doctor.

Indication

Fibrinolysis
in menorrhagia, epistaxis, traumatic hyphema, neoplasma, obstetric complications, and other surgical procedures including bladder surgery, prostatectomy or conization of the cervix.
Tooth extraction
in patients with hemophilia and prophylactic treatment of hereditary angioedema

Dosage

LOCAL FIBRINOLYSIS
Hereditary angioneurotic edema, 500-1000 mg tranexamic acid by slow intravenous injection (maximum 100 mg/min; 2 ml/min for TRANEXID 250 mg/5 ml; 1 ml/min for TRANEXID 500 mg/5 ml) 3 times daily. For the treatment more than 3 days, it should be considered to use an oral tranexamic acid.

TOOTH EXTRACTION IN PATIENTS WITH HEMOPHILIA
— Immediately before tooth extraction:
Intravenous, 10 mg/kg of body weight

— Postsurgical:
25 mg/kg of body weight (orally) 3-4 times daily for 2-8 days (for patient unable to take medication orally, intravenous therapy, 10 mg/kg of body weight, 3-4 daily)

POSTSURGICAL HEMORRHAGE
1 gram 3 times daily, slow intravenous injection, administered for the first 3 days. Therapy is then continued, using 1 gram tranexamic acid orally 3-4 times daily (starts on the fourth day after surgery until macroscopic hematuria is no longer present).

PATIENTS WITH RENAL FUNCTION DISORDERS
– Serum creatinine 120-250 micromol/l (1.36-2.83 mg/dl):
IV Dose 10 mg/kg, 2 times daily.

– Serum creatinine 250-500 micromol/l (2.83-5.66 mg/dl):
IV Dose 10 mg/kg, once daily.

– Serum creatinine >500 micromol/l (>5.66 mg/dl):
IV Dose 10 mg/kg, every 48 hours or 5 mg/kg every 24 hours.