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Volequin 500mg tablets

Dexa Medica

Ingredients in every tablet

Levofloxacin 500 mg

Each package contains

1 strip of 10 tablets

Dosage form

tablet

Dosage formTablet; coated

Flavour

None

W.H.O. classification

J01M
J01M

A.T.C. Level 1

Anatomical Main group

J - Antiinfectives for systemic use
J01M

A.T.C. Level 2

Therapeutic subgroup

J01 - Antibacterials for Systemic Use
J01M

A.T.C. Level 3

Pharmacological subgroup

J01M - Quinolone Antibacterials

Available in

Myanmar
Cambodia

Warnings

Alcohol

CONSULT YOUR DOCTORSafety of this item for use with alcohol has not been established. Please consult your doctor.

Machinery

CAUTIONThis item may not be safe for use while operating heavy machinery. Use with caution and after consultation with your doctor.

Pregnancy

NOT RECOMMENDEDThis item is not safe for use during pregnancy.

Lactation

NOT RECOMMENDEDThis item is not safe for use during lactation.

Indication

Levofloxacin hemihydrate is indicated for adults (≥18 years) in infections with susceptible microorganism, such as:
Acute maxillary sinusitis
Acute bacterial exacerbations of chronic bronchitis
Community-acquired pneumonia
Uncomplicated skin and skin structure infections
Complicated urinary tract infection
Acute pyelonephritis
Culture and susceptibility testing performed periodically during therapy will provide information about the continued susceptibility of the pathogens to the antimicrobial agent and also the possible emergence of bacterial resistance.

Dosage

0 TO 18 YEARS OLD
The safety and efficacy of levofloxacin in pediatric patients and adolescents (<18 years) have not been established:

18 TO 65 YEARS OLD
Usual dose in patients with normal renal function (creatinine clearance >80 ml/minute) is 250-500 mg once daily. The dosage can be used usually for 7-14 days depending on the severity of the disease.
Acute bacterial exacerbation of chronic bronchitis
500 mg per 24 hours for 7 days.

Community-acquired pneumonia
500 mg per 24 hours for 7-14 days.

Acute maxillary sinusitis
500 mg per 24 hours for 10-14 days.

Uncomplicated skin and skin structure infection
500 mg per 24 hours for 7-10 days.

Complicated urinary tract infections (UTI)
250 mg per 24 hours for 10 days.

Acute pyelonephritis
250 mg per 24 hours for 10 days.

ADMINISTRATION
Levofloxacin tablet can be taken with or without regard to meals. Patients should be advised to drink fluid liberally.

PATIENTS WITH IMPAIRED RENAL FUNCTION
Patients with impaired renal function, with acute bacterial exacerbation of chronic bronchitis, community-acquired pneumonia, acute maxillary sinusitis, uncomplicated skin structure and skin infection, the dose should be given as follows:
Creatinine clearance 50-80 ml/minute
No dosage adjustment required.

Creatinine clearance 20-49 ml/minute
Initial dose: 500 mg.
Subsequent dose: 250 mg per 24 hours.

Creatinine clearance 10-19 ml/minute
Initial dose: 500 mg.
Subsequent dose: 250 mg per 48 hours.

Hemodialysis
Initial dose: 500 mg.
Subsequent dose: 250 mg per 48 hours.

CAPD (Chronic Ambulatory Peritoneal Dialysis)
Initial dose: 500 mg.
Subsequent dose: 250 mg per 48 hours.

Patients with impaired renal function, with complicated urinary tract infection, acute pyelonephritis, the dosage should be given as follow:
Creatinine clearance ≥20 ml/minute
No dosage adjustment required.

Creatinine clearance 10-19 ml/minute
Initial dose: 250 mg.
Subsequent dose: 250 mg per 48 hours.