Fladex
Indonesia • Dexa Medica
Indication
- Urethritis and vaginitis due to Trichomonas vaginalis.
- Amoebiasis (intestinal and hepatic amoebiasis).
- Prevention of postoperative anaerobic infections.
- Giardiasis due to Giardia lambliasis.
Composition
Each ml contains:
Metronidazole 5 mg
Package
Dosage Forms
IV InfusionATC Classification
Warning
Used with caution in patients with central nervous system diseases. Disturbances of central nervous system has been reported in some cases but disappeared if therapy is discontinued or dose decreased.
Taking alcohol during metronidazole therapy may cause abdominal cramps, nausea, vomiting, headache, flushing.
In prolonged metronidazole administration, it is recommended to perform hematological tests.
Dosage should be reduced and administered with caution to patients with hepatic diseases.
Safety and effectiveness in pediatric patients have not been established, except in the treatment of amoebiasis.
Dosage
Administration:
Intravenous infusion at the rate of 5 ml per minute has to be replaced soon with oral administration.
Treatment of infections in which bacteria have been identified:
In patient whom oral medication is not possible.
Adults and children <12 years:
- Adults: 500 mg by IV infusion every 8 hours.
- Children: 7.5 mg/kg body weight every 8 hours.
Prevention of postoperative abdominal infections (especially colorectal), gynecology:
- Adults: 500 mg by IV infusion before operation, followed by 500 mg oral medication every 8 hours as soon as this becomes feasible.
- Children: 7.5 mg/kg body weight (1.5 ml/kg body weight) every 8 hours.