Treatment of infections caused by susceptible microorganisms, i.e.:
- Urinary infections without complications caused by Escherichia coli and Proteus mirabilis.
- Otitis media caused by Haemophilus influenzae (ß-lactamase positive and negative strains), Moraxella (Branhamella) Catarrhalis (most of which are ß-lactamase positive) and Streptococcus pyogenes.
- Pharyngitis and Tonsillitis caused by Streptococcus pyogenes.
- Acute Bronchitis and acute exacerbation of chronic Bronchitis caused by Streptococcus pneumoniae and Haemophilus influenzae (ß-lactamase positive and negative strains).
Cefixime 100 mg
Up to 18 Years
The usual daily dose for pediatric:
1.5-3 mg (0.075-0.15 ml of Gracefix dry syrup)/kg body weight given orally twice a day. Dosage should be adjusted according to the condition of the patients.
For severe infections:
The dosage may be increased up to 6 mg (0.3 ml of Gracefix dry syrup)/kg body weight given twice a day.
In pediatrics with otitis media, it is recommended to treat with Gracefix dry syrup.
Patients with Impaired Renal Function
Patients with impaired renal function need a dosage adjustment depending on the degree of renal impairment. Recommended dosage: 75% of the standard dosage (i.e. 300 mg a day) if creatinine clearance is between 21 and 60 ml/minute or for patients on renal hemodialysis and 50% of the standard dosage (i.e. 200 mg a day) if creatinine clearance is <20 ml/minute or for patients on continuous ambulatory dialysis.