Medixon 125 mg
Indication
- Endocrine disorders
- Allergic disorders
- Gangguan disorders
- Dermatologic disorders
- Gastrointestinal disorders
- Hematologic disorders
- Hepatic diseases
- Nonrheumatoid inflammation
- Neoplastic diseases
- Nephrotic syndrome
- Neurologic diseases
- Neurotrauma
- Ophthalmic disorders
- Pericarditis
- Nasal polyps
- Respiratory disorders
Composition
Methylprednisolone 125 mg
Package
Dosage Forms
ATC Classification
Warning
Dosage
Up to 18 Years Old
Adrenocortical insufficiency:
Intramuscular, 0.18 mg (base) per kg of body weight or 3.33 mg (base) per square meter of body surface area daily (in three divided doses) every third day.
Acute spinal cord injury treatment:
intravenous, 30 mg (base) per kg of body weight administered over a 15 minutes, followed after 45 minutes by a continuous infusion of 5.4 mg per kg of body weight per hour, for 23 hours.
Adjunctive treatment in patients with Pneumocystis Carinii Pneumonia associated with AIDS:
- Children up to 14 years of age: dosage has not been established.
- Children 14 years of age or older: see Adults and adolescent dose.
Other indications:
Intramuscular, 0.14-0.84 mg (base) per kg of body weight or 4.16-25 mg (base) per square meter of body surface every 12 to 24 hours.
18 Years Old and Above
IM or IV, 10-40 mg (base), repeated as needed.
High dose (pulse therapy):
IV, 30 mg (base) per kg of body weight administered over at least 30 minutes. This dose may be repeated every 4-6 hours for 48 hours.
Acute exacerbations of multiple sclerosis:
intramuscular or intravenous, 160 mg (base) daily for 1 week, followed by 64 mg (base) every other day for 1 month.
Acute spinal cord injury treatment:
intravenous, 30 mg (base) per kg of body weight administered over 15 minutes, followed after 45 minutes by a continuous infusion of 5.4mg per kg of body weight per hour, for 23 hours.
Adjunctive treatment in patients with Pneumocystis carinii pneumonia associated with AIDS:
intravenous, 30 mg (base) twice daily on days one through five, 30 mg once daily on days six through ten, and 15 mg once daily on days eleven through twenty-one.
Direction for Use
IM or IV injection:
Reconstitute powder by adding solvent (containing benzyl alcohol 0.9%), mix homogeneously. Direct intravenously can be given at least 1 minute or can be given by intravenously infusion in dextrose 5%, NaCl 0.9% or dextrose 5% in NaCl 0.9% for at least 30 minutes. The solution is stable physically and chemically for 48 hours.