OMZ
Indication
- Short-term treatment of duodenal ulcers and which is unresponsive to H2 receptor antagonist drugs
- Short-term treatment of peptic ulcers
- Treatment of erosive/ulcerative esophagitis reflux that has been diagnosed by endoscopy
- Long-term treatment of Zollinger-Ellison syndrome
Composition
Omeprazole 20 mg
Package
Dosage Forms
ATC Classification
Warning
Dosage
Up to 18 Years
There has been no experience using omeprazole in children.
18 Years Old and Above
Recommended dose:
20 mg or 40 mg once daily, swallowed whole with water.
Omeprazole capsule should be taken before meal. The whole capsules should not be opened, chewed, or crushed and should be swallowed.
Patients with duodenal ulcer symptoms:
Treatment and healing may take 2 weeks. Patients who have not recovered within this initial treatment, usually require additional 2 weeks of therapy.
Patients with peptic ulcers or erosive/ulcerative esophagitis reflux symptoms:
Treatment and healing may take 4 weeks. Patients who have not recovered usually require additional 4 weeks of treatment.
Patients with refractory to other medications:
40 mg once daily and the healing usually attained within 4 weeks (for duodenal ulcer patients) or 8 weeks (for peptic ulcer or erosive/ulcerative esophagitis reflux).
Patients with Zollinger-Ellison syndrome:
Initial dose is 20-160 mg once daily, the dose should be adjusted individually and treatment should be given as long as clinically indicated. Dose higher than 80 mg per day should be divided, twice daily.
Elderly Patients
No dose adjustment is required.
Patients with Hepatic Impairment
No need for special doses.
Patients with Renal Impairment
No need for special doses.